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Merck

BRAF

v-raf murine sarcoma viral oncogene homolog B

Synonyms:
B-RAF1, BRAF1, NS7, RAFB1
Species:
Human BRAF (673), Mouse Braf (109880), Rat Braf (114486), Zebrafish braf (403065), cow BRAF (536051), Horse BRAF (100065760), domestic cat BRAF (101092346), dog BRAF (475526), chicken BRAF (396239), naked mole-rat Braf (101702762) ...More
UniProtKB ID:
P15056, A4D1T4, B6HY61, B6HY62, B6HY63, B6HY64, B6HY65, B6HY66
Gene ID:
  • Human(673) Summary: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(109880) Braf transforming gene
  • Rat(114486) v-raf murine sarcoma viral oncogene homolog B
  • Zebrafish(403065) v-raf murine sarcoma viral oncogene homolog B1
  • cow(536051) v-raf murine sarcoma viral oncogene homolog B
  • Horse(100065760) v-raf murine sarcoma viral oncogene homolog B1
  • domestic cat(101092346) v-raf murine sarcoma viral oncogene homolog B1
  • dog(475526) v-raf murine sarcoma viral oncogene homolog B1
  • chicken(396239) v-raf murine sarcoma viral oncogene homolog B1
  • naked mole-rat(101702762) v-raf murine sarcoma viral oncogene homolog B1
  • domestic guinea pig(100717765) v-raf murine sarcoma viral oncogene homolog B1
  • sheep(101107438) v-raf murine sarcoma viral oncogene homolog B1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
07-453
Anti-B-Raf Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot