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Merck

BMP8B

bone morphogenetic protein 8b

Synonyms:
BMP8, OP2
Species:
Human BMP8B (656), Mouse Bmp8b (12164), Rat Bmp8b (679119), sheep BMP8B (101120626), chicken BMP8B (771058), cow BMP8B (100296238), dog BMP8B (607768)
UniProtKB ID:
P34820, Q53ZM7, Q9NUF0
Gene ID:
  • Human(656) Summary: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]
  • Mouse(12164) bone morphogenetic protein 8b
  • Rat(679119) bone morphogenetic protein 8b
  • sheep(101120626) bone morphogenetic protein 8b
  • chicken(771058) bone morphogenetic protein 8b
  • cow(100296238) bone morphogenetic protein 8b
  • dog(607768) bone morphogenetic protein 8b

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