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Merck

BIRC5

baculoviral IAP repeat containing 5

Synonyms:
API4, EPR-1
Species:
Human BIRC5 (332), Mouse Birc5 (11799), Rat Birc5 (64041), chicken BIRC5 (374078), dog BIRC5 (442936), cow BIRC5 (414925), Horse BIRC5 (100050808), domestic cat BIRC5 (493835), sheep BIRC5 (101123390), naked mole-rat Birc5 (101703201)
UniProtKB ID:
O15392, A2SUH6, B2R4R1, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2
Gene ID:
  • Human(332) Summary: This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
  • Mouse(11799) baculoviral IAP repeat-containing 5
  • Rat(64041) baculoviral IAP repeat-containing 5
  • chicken(374078) baculoviral IAP repeat containing 5
  • dog(442936) baculoviral IAP repeat containing 5
  • cow(414925) baculoviral IAP repeat containing 5
  • Horse(100050808) baculoviral IAP repeat containing 5
  • domestic cat(493835) baculoviral IAP repeat containing 5
  • sheep(101123390) baculoviral IAP repeat containing 5
  • naked mole-rat(101703201) baculoviral IAP repeat containing 5
  • domestic guinea pig(100527953) baculoviral IAP repeat-containing 5

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Antibodies

Product Number
Description
Species Reactivity
Application
AB3610
Anti-Survivin Antibody, serum, Chemicon®,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot