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Merck

BAIAP2

BAI1-associated protein 2

Synonyms:
BAP2, FLAF3, IRSP53
Species:
Human BAIAP2 (10458), Mouse Baiap2 (108100), Rat Baiap2 (117542), sheep BAIAP2 (101109895), domestic guinea pig Baiap2 (100734135), naked mole-rat Baiap2 (101697688), chicken BAIAP2 (422077), domestic cat BAIAP2 (101087366), dog BAIAP2 (403473), cow BAIAP2 (507837)
UniProtKB ID:
Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43
Gene ID:
  • Human(10458) Summary: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
  • Mouse(108100) brain-specific angiogenesis inhibitor 1-associated protein 2
  • Rat(117542) BAI1-associated protein 2
  • sheep(101109895) BAI1-associated protein 2
  • domestic guinea pig(100734135) BAI1-associated protein 2
  • naked mole-rat(101697688) BAI1-associated protein 2
  • chicken(422077) BAI1-associated protein 2
  • domestic cat(101087366) BAI1-associated protein 2
  • dog(403473) BAI1-associated protein 2
  • cow(507837) BAI1-associated protein 2

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