ASCL1
achaete-scute complex homolog 1 (Drosophila)
Synonyms:
ASH1, HASH1, MASH1, bHLHa46
Species:
Human ASCL1 (429), Mouse Ascl1 (17172), Rat Ascl1 (64186), chicken ASCL1 (386573), cow ASCL1 (540473), domestic cat ASCL1 (101081993), dog ASCL1 (482628), sheep ASCL1 (101110666), domestic guinea pig Ascl1 (100734843), naked mole-rat Ascl1 (101704178)
UniProtKB ID:
Gene ID:
- Human(429) Summary: This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]
- Mouse(17172) achaete-scute complex homolog 1 (Drosophila)
- Rat(64186) achaete-scute complex homolog 1 (Drosophila)
- chicken(386573) achaete-scute complex homolog 1 (Drosophila)
- cow(540473) achaete-scute complex homolog 1 (Drosophila)
- domestic cat(101081993) achaete-scute complex homolog 1 (Drosophila)
- dog(482628) achaete-scute complex homolog 1 (Drosophila)
- sheep(101110666) achaete-scute complex homolog 1 (Drosophila)
- domestic guinea pig(100734843) achaete-scute complex homolog 1 (Drosophila)
- naked mole-rat(101704178) achaete-scute complex homolog 1 (Drosophila)
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