ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
Synonyms:
AC, ACDase, ASAH, PHP, PHP32, SMAPME
Species:
Human ASAH1 (427), Mouse Asah1 (11886), Rat Asah1 (84431), chicken ASAH1 (422727), cow ASAH1 (510620), domestic cat ASAH1 (101082231), dog ASAH1 (482897), naked mole-rat Asah1 (101724913), domestic guinea pig Asah1 (100735549), sheep ASAH1 (101117904)
UniProtKB ID:
Gene ID:
- Human(427) Summary: This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(11886) N-acylsphingosine amidohydrolase 1
- Rat(84431) N-acylsphingosine amidohydrolase (acid ceramidase) 1
- chicken(422727) N-acylsphingosine amidohydrolase (acid ceramidase) 1
- cow(510620) N-acylsphingosine amidohydrolase (acid ceramidase) 1
- domestic cat(101082231) N-acylsphingosine amidohydrolase (acid ceramidase) 1
- dog(482897) N-acylsphingosine amidohydrolase (acid ceramidase) 1
- naked mole-rat(101724913) N-acylsphingosine amidohydrolase (acid ceramidase) 1
- domestic guinea pig(100735549) N-acylsphingosine amidohydrolase (acid ceramidase) 1
- sheep(101117904) N-acylsphingosine amidohydrolase (acid ceramidase) 1
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