APLNR
apelin receptor
Synonyms:
AGTRL1, APJ, APJR, HG11
Species:
Human APLNR (187), Mouse Aplnr (23796), Rat Aplnr (83518), naked mole-rat Aplnr (101698984), domestic guinea pig Aplnr (100714001), sheep APLNR (101119419), Domestic Rabbit APLNR (100348126), chicken APLNR (429337), domestic cat APLNR (101088782), cow APLNR (615435)
UniProtKB ID:
Gene ID:
- Human(187) Summary: This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009]
- Mouse(23796) apelin receptor
- Rat(83518) apelin receptor
- naked mole-rat(101698984) apelin receptor
- domestic guinea pig(100714001) apelin receptor
- sheep(101119419) apelin receptor
- Domestic Rabbit(100348126) apelin receptor
- chicken(429337) apelin receptor
- domestic cat(101088782) apelin receptor
- cow(615435) apelin receptor
- dog(483497) apelin receptor
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