ALDH5A1
aldehyde dehydrogenase 5 family, member A1
Synonyms:
SSADH, SSDH
Species:
Human ALDH5A1 (7915), Mouse Aldh5a1 (214579), Rat Aldh5a1 (291133), naked mole-rat Aldh5a1 (101723101), domestic guinea pig Aldh5a1 (100735182), sheep ALDH5A1 (101107828), Domestic Rabbit ALDH5A1 (100351836), Zebrafish aldh5a1 (565235), cow ALDH5A1 (532724), domestic cat ALDH5A1 (101088238) ...More
UniProtKB ID:
Gene ID:
- Human(7915) Summary: This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(214579) aldhehyde dehydrogenase family 5, subfamily A1
- Rat(291133) aldehyde dehydrogenase 5 family, member A1
- naked mole-rat(101723101) aldehyde dehydrogenase 5 family, member A1
- domestic guinea pig(100735182) aldehyde dehydrogenase 5 family, member A1
- sheep(101107828) aldehyde dehydrogenase 5 family, member A1
- Domestic Rabbit(100351836) aldehyde dehydrogenase 5 family, member A1
- Zebrafish(565235) aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)
- cow(532724) aldehyde dehydrogenase 5 family, member A1
- domestic cat(101088238) aldehyde dehydrogenase 5 family, member A1
- dog(488246) aldehyde dehydrogenase 5 family, member A1
- chicken(420818) aldehyde dehydrogenase 5 family, member A1
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Small Molecule - Inhibitor
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