ADRBK1
adrenergic, beta, receptor kinase 1
Synonyms:
BARK1, BETA-ARK1, GRK2
Species:
Human ADRBK1 (156), Mouse Adrbk1 (110355), Rat Adrbk1 (25238), chicken ADRBK1 (426000), dog ADRBK1 (483701), domestic cat ADRBK1 (101101082), cow ADRBK1 (282682), domestic guinea pig Adrbk1 (100732560), naked mole-rat Adrbk1 (101708906), sheep ADRBK1 (101108265)
UniProtKB ID:
Gene ID:
- Human(156) Summary: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]
- Mouse(110355) adrenergic receptor kinase, beta 1
- Rat(25238) adrenergic, beta, receptor kinase 1
- chicken(426000) adrenergic, beta, receptor kinase 1
- dog(483701) adrenergic, beta, receptor kinase 1
- domestic cat(101101082) adrenergic, beta, receptor kinase 1
- cow(282682) adrenergic, beta, receptor kinase 1
- domestic guinea pig(100732560) adrenergic, beta, receptor kinase 1
- naked mole-rat(101708906) adrenergic, beta, receptor kinase 1
- sheep(101108265) adrenergic, beta, receptor kinase 1
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