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Merck

ADRB2

adrenoceptor beta 2, surface

Synonyms:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Species:
UniProtKB ID:
Gene ID:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface

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Small Molecule - Agonist

Product Number
Description
Species
Albuterol sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Metaproterenol sulfate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Salbutamol sulfate, European Pharmacopoeia (EP) Reference Standard,
Species
human
Salmeterol xinafoate for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Orciprenaline for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Propranolol hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Propranolol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Timolol maleate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Timolol maleate, British Pharmacopoeia (BP) Reference Standard,
Species
human
Timolol maleate, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Blocker

Product Number
Description
Species
Sotalol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
Propafenone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Propafenone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human