ADRB2
adrenoceptor beta 2, surface
Synonyms:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Species:
Human ADRB2 (154), Mouse Adrb2 (11555), Rat Adrb2 (24176), domestic guinea pig Adrb2 (100722663), naked mole-rat Adrb2 (101708921), sheep ADRB2 (100170320), Domestic Rabbit ADRB2 (100340821), chicken ADRB2 (427623), domestic cat ADRB2 (493767), cow ADRB2 (281605) ...More
UniProtKB ID:
Gene ID:
- Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
- Mouse(11555) adrenergic receptor, beta 2
- Rat(24176) adrenoceptor beta 2, surface
- domestic guinea pig(100722663) adrenoceptor beta 2, surface
- naked mole-rat(101708921) adrenoceptor beta 2, surface
- sheep(100170320) adrenoceptor beta 2, surface
- Domestic Rabbit(100340821) adrenoceptor beta 2, surface
- chicken(427623) adrenergic, beta-2-, receptor, surface
- domestic cat(493767) adrenoceptor beta 2, surface
- cow(281605) adrenergic, beta-2-, receptor, surface
- Horse(100060659) adrenoceptor beta 2, surface
- dog(403910) adrenoceptor beta 2, surface
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Small Molecule - Agonist
Product Number
Description
Species
Albuterol sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Salbutamol sulfate for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Antagonist
Product Number
Description
Species
Propranolol hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Carvedilol for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human