ADM
adrenomedullin
Synonyms:
AM
Species:
Human ADM (133), Mouse Adm (11535), Rat Adm (25026), fruit fly adm (250086), domestic cat ADM (101087095), cow ADM (280713), dog ADM (403817), chicken ADM (423042), naked mole-rat Adm (101705917), domestic guinea pig Adm (100733203)
UniProtKB ID:
Gene ID:
- Human(133) Summary: Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element. [provided by RefSeq, Jul 2008]
- Mouse(11535) adrenomedullin
- Rat(25026) adrenomedullin
- fruit fly(250086) all discs missing
- domestic cat(101087095) adrenomedullin
- cow(280713) adrenomedullin
- dog(403817) adrenomedullin
- chicken(423042) adrenomedullin
- naked mole-rat(101705917) adrenomedullin
- domestic guinea pig(100733203) adrenomedullin
- sheep(101103753) adrenomedullin
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