Y0001519

Pioglitazone for system suitability

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): Pioglitazone hydrochloride, 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride
• Empirical Formula (Hill Notation): C₁₉H₂₀N₂O₃S · HCl
• CAS Number: 112529-15-4
• Molecular Weight: 392.90
• MDL number: MFCD04975446
• UNSPSC Code: 41116107
• PubChem Substance ID: 329831470
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: pioglitazone
• manufacturer/tradename: EDQM
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1
• InChI: 1S/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H
• InChI key: GHUUBYQTCDQWRA-UHFFFAOYSA-N
• Gene Information: human ... PPARG(5468)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pioglitazone for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Pioglitazone hydrochloride is a PPARγ agonist and thiazolidinedione (TZD) anti-diabetic. Pioglitazone is a selective agonist of the nuclear receptor peroxisome proliferator-activated receptor γ (PPAR-γ) and to a lesser extent PPAR-α.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable