T-046

Testosterone-d₃ (16, 16, 17-d₃) solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonym(s): Testosterone-d₃ solution
• CAS Number: 77546-39-5
• EC Number: 200-835-2
• MDL number: MFCD00079586
• UNSPSC Code: 41116107
• PubChem Substance ID: 329826606
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in acetonitrile
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: [H]C1([H])C[C@]2([H])[C@@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@]3([H])CC[C@@]2(C)[C@]1([H])O
• InChI: 1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1/i6D2,17D
• InChI key: MUMGGOZAMZWBJJ-HZRGXLBSSA-N

Description

General description

A stable-labeled internal standard for testosterone testing or isotope dilution methods by GC/MS or LC/MS for sports testing, urine drug testing or diagnostic testing by LC-MS/MS or GC/MS. Testosterone, a hormone from the androgen group, is an important sex hormone and anabolic steroid used as a performance enhancing drug.

Application

• First detection/quantification of roxadustat in hair with a new liquid chromatography with tandem mass spectrometry method: This study highlights the advanced LC-MS/MS methodologies that can be adapted for the detection and quantification of deuterated compounds like Testosterone-d₃ in biological samples, providing precision in pharmacokinetic studies (Alvarez et al., 2023).


• A quantitative method for the simultaneous detection of SR9009 and SR9011 in equine plasma: Demonstrates the application of liquid chromatography-electrospray ionization-tandem mass spectrometry, a technique that can be used for accurately measuring stable isotope-labeled compounds such as Testosterone-d₃ in complex matrices (Kwak et al., 2022).


• Collision energy-breakdown curves - An additional tool to characterize MS/MS methods: Discusses the optimization of mass spectrometry parameters which can enhance the detection of deuterated drugs like Testosterone-d₃, crucial for detailed metabolic studies (Mörlein et al., 2020).


• Detection and quantification of 12 anabolic steroids and analogs in human whole blood and 20 in hair using LC-HRMS/MS: Explores high-resolution mass spectrometry for detecting substances in biological samples, relevant for the precise analysis of Testosterone-d₃ in doping control and clinical research (Fabresse et al., 2017).


• Determination of anabolic agents in dietary supplements by liquid chromatography-high-resolution mass spectrometry: Focuses on the reliable identification of performance-enhancing drugs, which can include the application of Testosterone-d₃ as an internal standard to ensure accuracy and traceability in analytical testing (Odoardi et al., 2015).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332,H319
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 35.6 °F - closed cup
• Flash Point(C): 2 °C - closed cup