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EZH2

enhancer of zeste homolog 2 (Drosophila)

Synonyms:
ENX-1, ENX1, EZH1, EZH2b, KMT6, KMT6A, WVS, WVS2
Species:
UniProtKB ID:
Gene ID:
  • Human(2146) Summary: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(14056) enhancer of zeste homolog 2 (Drosophila)
  • Rat(312299) enhancer of zeste homolog 2 (Drosophila)
  • Zebrafish(768133) enhancer of zeste homolog 2 (Drosophila)
  • chicken(420784) enhancer of zeste homolog 2 (Drosophila)
  • domestic cat(101087309) enhancer of zeste homolog 2 (Drosophila)
  • cow(509106) enhancer of zeste homolog 2 (Drosophila)
  • Horse(100051290) enhancer of zeste homolog 2 (Drosophila)
  • dog(475511) enhancer of zeste homolog 2 (Drosophila)
  • naked mole-rat(101702710) enhancer of zeste homolog 2 (Drosophila)
  • domestic guinea pig(100713765) enhancer of zeste homolog 2 (Drosophila)
  • sheep(101120745) enhancer of zeste homolog 2 (Drosophila)
  • Domestic Rabbit(100345157) enhancer of zeste homolog 2 (Drosophila)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-EZH2 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP129, affinity isolated antibody,
Species Reactivity
frog, human, monkey, mouse, rat
Application
flow cytometry
immunohistochemistry

western blot
ChIPAb+ EZH2, clone AC22 - ChIP Validated Antibody and Primer Set, clone AC22, from mouse,
Species Reactivity
human, mouse, rat, vertebrates
Application
ChIP
western blot
Anti-EZH2 Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse
Application
ChIP
immunoprecipitation (IP)

western blot
Anti-EZH2 Antibody, clone 6I10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, horse, human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-EZH2 Antibody, serum, Upstate®,
Species Reactivity
human, mouse, rat
Application
western blot

Proteins

Product Number
Description
Species
EZH2 / EED / SUZ12 human, recombinant, expressed in baculovirus infected insect cells, ≥90% (SDS-PAGE),
Species
human
EZH2/EED inactive  human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Species
human
EZH2 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥49% (SDS-PAGE),
Species
human
EZH2/SUZ12/RbAp48 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥88% (SDS-PAGE),
Species
human
EZH2 /EED/SUZ12/RbAp48/AEBP2 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ezh2,
Species
mouse
MISSION® esiRNA, targeting human EZH2,
Species
human