BLNK
B-cell linker
Synonyms:
AGM4, BASH, BLNK-S, LY57, SLP-65, SLP65, bca
Species:
Human BLNK (29760), Mouse Blnk (17060), Rat Blnk (499356), Zebrafish blnk (405764), chicken BLNK (395733), dog BLNK (486814), cow BLNK (510393), Horse BLNK (100070841), domestic cat BLNK (101086423), naked mole-rat Blnk (101718500) ...More
UniProtKB ID:
Gene ID:
- Human(29760) Summary: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
- Mouse(17060) B cell linker
- Rat(499356) B-cell linker
- Zebrafish(405764) B-cell linker
- chicken(395733) B-cell linker
- dog(486814) B-cell linker
- cow(510393) B-cell linker
- Horse(100070841) B-cell linker
- domestic cat(101086423) B-cell linker
- naked mole-rat(101718500) B-cell linker
- domestic guinea pig(100712978) B-cell linker
- sheep(101111241) B-cell linker
Custom & Knockdown Gene Products
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Ms Blnk antibody produced in rabbit, ,
Species Reactivity
mouse
Application
western blot
Anti-BLNK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-BLNK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-BLNK antibody produced in mouse, clone 1D7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
proximity ligation assay
western blot
proximity ligation assay
western blot
Anti-phospho-BLNK (pTyr96) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
PrEST Antigen BLNK, Prestige Antigens™ Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
PrEST Antigen BLNK, Prestige Antigens™ Powered by Atlas Antibodies, buffered aqueous solution,
Species
human