Skip to Content
Merck

ALDOB

aldolase B, fructose-bisphosphate

Synonyms:
ALDB, ALDO2
Species:
UniProtKB ID:
Gene ID:
  • Human(229) Summary: Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]
  • Mouse(230163) aldolase B, fructose-bisphosphate
  • Rat(24190) aldolase B, fructose-bisphosphate
  • domestic guinea pig(100720708) aldolase B, fructose-bisphosphate
  • naked mole-rat(101713582) aldolase B, fructose-bisphosphate
  • sheep(443440) aldolase B, fructose-bisphosphate
  • Domestic Rabbit(100328925) aldolase B, fructose-bisphosphate
  • Zebrafish(321664) aldolase b, fructose-bisphosphate
  • cow(515263) aldolase B, fructose-bisphosphate
  • Horse(100054480) aldolase B, fructose-bisphosphate
  • domestic cat(101097025) aldolase B, fructose-bisphosphate
  • dog(474787) aldolase B, fructose-bisphosphate
  • chicken(427308) aldolase B, fructose-bisphosphate

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ALDOB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-ALDOB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ALDOB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-ALDOB antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-ALDOB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Kits

Product Number
Description
Species
Aldolase Activity Colorimetric Assay Kit, Sufficient for 100 Colorimetric tests,
Species
mouse, human, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ALDOB,
Species
human