Comparison of oral dydrogestrone with progesterone gel and micronized progesterone for luteal support in 1,373 women undergoing in vitro fertilization: a randomized clinical study.

To compare the efficacy of oral dydrogesterone with that of micronized vaginal P gel and micronized P capsule for luteal supplementation. Prospective, randomized clinical study. Institute of Reproductive Medicine, Kolkata, India. A total of 1,373 infertile women undergoing IVF participated. Micronized P gel, P capsule, and oral dydrogesterone were administered for luteal support and compared. Demographic profile and pregnancy and miscarriage rates. The overall pregnancy rate and miscarriage rate were comparable among the three groups. Oral dydrogesterone seems to be a promising drug for luteal support in woman undergoing IVF.