Skip to Content
Merck
HomeServicesCustom ProductsCustom HPLC Column Request

Custom HPLC Column Request

Browse our HPLC and UHPLC columns for greater separation process

Our wide selection of HPLC columns for small and large molecule analysis enhances the separation process in terms of retention, resolution, selectivity, and analysis time, all while reducing the time for method development.

We also offer custom-packed columns to give you the maximum flexibility in your HPLC applications. With our customized packing system, our multiple particles, chemistry options, and column hardware are available in different combinations.

Please use this form to request a quote for a custom HPLC column.

Related Product Resources

Brochure: Chromolith
Brochure: Bioshell® Columns
Brochure: Purospher STAR Columns

Related Product Categories
Solvents
Your Solvent Source: Find the right fit with Supelco®, SigmaAldrich®, & SAFC® brands, covering analytical, lab, & biopharmaceutical uses. Order online.
HPLC Buffers
Choose the right HPLC grade buffers for precise reversed-phase chromatography. Explore our selection now.
Chromatography Standards
Certified Reference Materials & reference standards for chromatography-based testing applications including forensic and clinical toxicology analysis, diagnostic testing, therapeutic drug monitoring, cannabis testing, environmental analysis, pharmaceutical research, and food & beverage testing.
Certified Reference Materials
Browse our Certified Reference Materials (CRMs) for applications in forensic and clinical toxicology analysis, diagnostic testing, therapeutic drug monitoring, cannabis testing, environmental analysis, pharmaceutical research, and food & beverage testing.
Solid Phase Extraction & QuEChERS
Browse our website for the full range of systems, devices, and materials for solid phase extraction (SPE) products including cartridges, glass tubes, 96-well plates, QuEChERS tubes (dispersive SPE), online SPE, and vacuum manifolds for all of your scientific needs.
Supported Liquid Extraction Columns, Resins & Accessories
Explore our selection of EXtrelut® NT sorbents and columns to simplify your liquid-liquid extraction (LLE) based methods by replacing separatory funnels.
Related Applications
Solid Phase Extraction (SPE)
Solid phase extraction (SPE) is a technique used for rapid, selective sample preparation and purification prior to chromatographic analysis (e.g. HPLC, GC, TLC). SPE is used to exchange sample matrices, concentrate analytes, and remove interferences and contaminants to improve data and protect the analytical column.
Mass Spectrometry
Mass spectrometry (MS) is an analytical tool used to identify compounds, determine chemical structure, and assess isotopic abundance. In MS, samples are ionized, and the resulting ions are identified based on their mass-to-charge (m/z) ratios.
Low Pressure Liquid Chromatography
Low pressure liquid chromatography (LPLC) is a chromatographic technique that operates at low pressures to drive the mobile phase onto the column containing a stationary phase by the action of a pump.
Small Molecule HPLC
Small molecules are ions and compounds of molecular weight typically less than 900 daltons. These compounds can be effectively separated and analyzed by HPLC, UHPLC and LC-MS using mainly silica particles or monolithic stationary phases with a broad range of column chemistries (modifications).
Large Molecule HPLC
High performance liquid chromatography (HPLC) can be used to separate and identify different large biomolecules such as protein and peptides in a sample. It is based on the pumping of a sample with a solvent (mobile phase) through a column packed with sorbent material (stationary phase) at a high pressure.
Sign In To Continue

To continue reading please sign in or create an account.

Don't Have An Account?