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Key Documents

19-160

Sigma-Aldrich

BrdU (5-Bromo-2′-deoxyuridine)

Used for the study of DNA synthesis where it is incorporated into DNA in place of thymidine, BrdU can be used in conjunction with anti-BrdU for immunocytochemical analysis of cell proliferation.

Synonym(s):

Bromodeoxyuridine

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About This Item

UNSPSC Code:
41116012
eCl@ss:
32160405
NACRES:
NA.41

Quality Level

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable

shipped in

wet ice

Application

Research Category
All
Used for the study of DNA synthesis where it is incorporated into DNA in place of thymidine; BrdU can be used in conjunction with anti-BrdU for immunocytochemical analysis of cell proliferation.

Physical form

C9H11BrN2O5

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Muta. 1B - Repr. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2


Certificates of Analysis (COA)

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Immunocytochemical detection of S-phase cells in normal and neoplastic cervical epithelium by anti-BrdU monoclonal antibody
Fukuda, K, et al
Analytical and Quantitative Cytology and Histology, 12, 135-138 (1990)
Maribel Huerta-Cervantes et al.
Nutrients, 12(2) (2020-02-07)
Gestational diabetes (GD) has been linked with an increased risk of developing metabolic disorders and behavioral abnormalities in the offspring. Oxidative stress is strongly associated with neurodegeneration and cognitive disruption. In the offspring brains in a GD experimental rat model
Gabriel Schneebauer et al.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 186(7), 867-877 (2016-05-06)
In a process called silvering, European eels prepare for their long-distance migration from European freshwater systems to the Sargasso Sea for reproduction. During this journey, eels perform extended diel vertical migrations, and the concomitant changes in hydrostatic pressure significantly affect
Ramzi A Al-Horani et al.
Journal of applied physiology (Bethesda, Md. : 1985), 126(4), 1110-1116 (2019-01-25)
Myocardial mitochondrial biogenesis and vascular angiogenesis biomarker responses to postexercise cold-water immersion (CWI) have not been reported. Therefore, to determine those cardiac adaptations, adult male Sprague-Dawley rats were divided into three groups: postexercise CWI (CWI; n = 13), exercise only
Uma Kizhuveetil et al.
Scientific reports, 10(1), 1588-1588 (2020-02-02)
Rhythms in the pseudo-steady state (PSS) levels of reactive species (RS), particularly superoxide and hydroxyl radicals, exist in cancer cells. The RS rhythm characteristics, particularly frequency and amplitude, are entrained (reset) by the anticancer compounds/drugs. In this work, we show

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