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Merck

STC2

stanniocalcin 2

Synonyms:
STC-2, STCRP
Species:
UniProtKB ID:
Gene ID:
  • Human(8614) Summary: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq, Jul 2008]
  • Mouse(20856) stanniocalcin 2
  • Rat(63878) stanniocalcin 2
  • chicken(416208) stanniocalcin 2
  • domestic cat(101090485) stanniocalcin 2
  • dog(489112) stanniocalcin 2
  • cow(540573) stanniocalcin 2
  • sheep(101109910) stanniocalcin 2
  • naked mole-rat(101723645) stanniocalcin 2
  • domestic guinea pig(100727509) stanniocalcin 2

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-STC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Stc2,
Species
mouse
MISSION® esiRNA, targeting human STC2,
Species
human