SF3B1
splicing factor 3b, subunit 1, 155kDa
Synonyms:
Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155
Species:
Human SF3B1 (23451), Mouse Sf3b1 (81898), Rat Sf3b1 (84486), Zebrafish sf3b1 (446117), dog SF3B1 (488456), Horse SF3B1 (100070506), domestic cat SF3B1 (101088016), chicken SF3B1 (424056), cow SF3B1 (510177), sheep SF3B1 (101121573) ...More
UniProtKB ID:
Gene ID:
- Human(23451) Summary: This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(81898) splicing factor 3b, subunit 1
- Rat(84486) splicing factor 3b, subunit 1
- Zebrafish(446117) splicing factor 3b, subunit 1
- dog(488456) splicing factor 3b, subunit 1, 155kDa
- Horse(100070506) splicing factor 3b, subunit 1, 155kDa
- domestic cat(101088016) splicing factor 3b, subunit 1, 155kDa
- chicken(424056) splicing factor 3b, subunit 1, 155kDa
- cow(510177) splicing factor 3b, subunit 1, 155kDa
- sheep(101121573) splicing factor 3b, subunit 1, 155kDa
- Goat(100861148) splicing factor 3b, subunit 1, 155kDa
- naked mole-rat(101707227) splicing factor 3b, subunit 1, 155kDa
- domestic guinea pig(100723509) splicing factor 3b, subunit 1, 155kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SF3B1, affinity isolated antibody,
Species Reactivity
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-SAP155/SF3b155 Antibody, serum, from rabbit,
Species Reactivity
bovine, human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-SF3B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SF3b155 (SAP 155) Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
western blot
western blot
Anti-SF3B1 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot