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Merck

SCN5A

sodium channel, voltage-gated, type V, alpha subunit

Synonyms:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Species:
UniProtKB ID:
Gene ID:
  • Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(20271) sodium channel, voltage-gated, type V, alpha
  • Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
  • chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
  • domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
  • Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
  • dog(403497) sodium channel, voltage-gated, type V, alpha subunit
  • domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
  • naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
  • Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
  • cow(282061) sodium channel, voltage-gated, type V, alpha subunit
  • sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SCN5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-SCN5A (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rat
Application
immunohistochemistry
western blot
Anti-SCN5A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-Sodium Channel NaV1.5 human antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
human
Application
western blot
Anti-Sodium Channel Nav1.5 Antibody, pain, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
Flecainide acetate salt, ,
Species
human
(±)-Flecainide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Flecainide acetate, European Pharmacopoeia (EP) Reference Standard,
Species
human
Flecainide acetate, British Pharmacopoeia (BP) Reference Standard,
Species
human
Flecainide acetate, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Lamotrigine, ≥98%, powder,
Species
rat, human
Carbamazepine, powder,
Species
rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SCN5A,
Species
human