PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Synonyms:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
Species:
Human PTGS2 (5743), Mouse Ptgs2 (19225), Rat Ptgs2 (29527), cow PTGS2 (282023), sheep PTGS2 (443460), Goat PTGS2 (100860905), naked mole-rat Ptgs2 (101704771), Domestic Rabbit PTGS2 (100009248), domestic guinea pig Ptgs2 (100135607), chicken PTGS2 (396451) ...More
UniProtKB ID:
Gene ID:
- Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
- Mouse(19225) prostaglandin-endoperoxide synthase 2
- Rat(29527) prostaglandin-endoperoxide synthase 2
- cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2
- chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
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ELISA
Product Number
Description
Species
Human COX-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-COX2/PTGS2 Antibody, clone 2V7G8, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
immunohistochemistry
western blot
western blot
Anti-Cyclooxygenase-2 Antibody, Chemicon®, from rabbit,
Species Reactivity
bovine, human, mouse, sheep
Application
ELISA
western blot
western blot
COX-2 (SP21) Rabbit Monoclonal Antibody, ,
Species Reactivity
human
Application
immunohistochemistry
Anti-PTGS2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-COX2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Blocker
Product Number
Description
Species
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
Cyclooxygenase 2 human, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
Species
human