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Merck

CHIT1

chitinase 1 (chitotriosidase)

Synonyms:
CHI3, CHIT, CHITD
Species:
UniProtKB ID:
Gene ID:
  • Human(1118) Summary: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(71884) chitinase 1 (chitotriosidase)
  • Rat(289032) chitinase 1 (chitotriosidase)
  • domestic cat(101081696) chitinase 1 (chitotriosidase)
  • cow(789394) chitinase 1 (chitotriosidase)
  • Horse(100065255) chitinase 1 (chitotriosidase)
  • naked mole-rat(101702614) chitinase 1 (chitotriosidase)
  • domestic guinea pig(100721444) chitinase 1 (chitotriosidase)
  • Domestic Rabbit(100338170) chitinase 1 (chitotriosidase)

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ELISA

Product Number
Description
Species
Human Chitotriosidase ELISA, for serum, plasma and cell culture supernatants,
Species
human

Activity Assay

Product Number
Description
Species
Chitinase Assay Kit, Fluorimetric, sufficient for 200 multiwell tests,
Species
human
Chitinase Assay Kit, sufficient for 100 multiwell tests,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CHIT1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-CHIT1 antibody produced in mouse, clone 1D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-CHIT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CHIT1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CHIT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Kits

Product Number
Description
Species
Chitinase Assay Kit, sufficient for 100 multiwell tests,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHIT1,
Species
human