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Merck

ARHGAP35

Rho GTPase activating protein 35

Synonyms:
GRF-1, GRLF1, P190-A, P190A, p190ARhoGAP, p190RhoGAP
Species:
UniProtKB ID:
Gene ID:
  • Human(2909) Summary: The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq, Jul 2008]
  • Rat(306400) Rho GTPase activating protein 35
  • Zebrafish(564565) Rho GTPase activating protein 35b
  • cow(540310) Rho GTPase activating protein 35
  • chicken(425730) Rho GTPase activating protein 35
  • dog(403543) Rho GTPase activating protein 35
  • domestic cat(101089912) Rho GTPase activating protein 35
  • sheep(101117354) Rho GTPase activating protein 35
  • domestic guinea pig(100718086) Rho GTPase activating protein 35
  • naked mole-rat(101719355) Rho GTPase activating protein 35

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-GRF-1 (pTyr1105) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-ARHGAP35 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-ARHGAP35 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ARHGAP35,
Species
human