Skip to Content
Merck
HomeApplicationsProtein BiologyLysis & Protein Extraction

Lysis & Protein Extraction

A digital illustration of multiple blue colored cells, representing human cells, suspended in a light blue environment.

When purifying proteins for functional or structural studies, or for preparative processing and production, the first step is to disrupt the cells or tissue to gain access to the target proteins. Cell lysis and protein solubilization are key to effective analysis and efficient processing. The choice of extraction method can be enzymatic, chemical, mechanical or a combination.



Featured Categories

Cell lysis for protein extraction.
Whole Cell Lysis Reagents & Enhancers

Protein extraction kits, cell lysis buffers, and reagents for solubilizing proteins from bacteria, yeast, and insect cultures, as well as plant and mammalian cell cultures and tissue samples.

Shop Products
A 3D rendering of intricate purple protein molecules floating against a deep blue background. The molecules vary in size and are scattered throughout, with a complex structure featuring multiple protrusions and cavities. They are highlighted by the lighting, giving them a glossy appearance..
Phosphatase and Protease Inhibitor Cocktails

Protease and phosphatase inhibitors and cocktails to prevent proteolysis and protein dephosphorylation, and to preserve the active state of proteins during cell lysis, protein extraction, and sample preparation.

Shop Products
Subcellular fractionation techniques
Subcellular Fractionation, Enrichment, and Depletion Reagents

Uncover proteins with precision: Explore kits for subcellular fractionation, protein enrichment, & extraction across diverse sample types in proteomics research.

Shop Products
Extreme close-up of detergent bubbles in different sizes
Detergents - Anionic, Cationic, Zwitterionic, Anti-foaming

Discover versatile biological detergents, surfactants for lysis, electrophoresis, WB, transfection, research applications. REACH-compliant options available.

Shop Products


Sign In To Continue

To continue reading please sign in or create an account.

Don't Have An Account?