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Merck

Cell Therapy Manufacturing

Commercializing a new cell therapy demands optimal performance at every stage: upstream processing, downstream processing, process development, testing and manufacturing services. On the cutting edge of regenerative medicine, biopharmaceutical manufacturers need a partner with a proven track record of advancing cellular therapy product development and manufacturing, as well as the ability to adapt to client needs. Thousands of sophisticated products and tools are used in support of these efforts, and any inefficiency can lead to bottlenecks that slow progress within highly compressed timelines. Consequently, each step in cell therapy manufacturing must meet rigorous standards of quality and efficiency. Solving these potential bottlenecks in cell therapy commercialization requires optimization of cell therapy manufacturing platforms, media and reagents, characterization tools, process development services, and testing.  



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Two technicians in a sterile environment are operating a Mobius 2D and 3D single-use assembly system. They are dressed in full protective cleanroom suits, complete with hoods and masks, ensuring a contamination-free process.
Single-Use Assemblies

Mobius® 2D and 3D single-use assemblies and systems for sterile fluid management offer flexible manufacturing options for biopharmaceutical companies, from media and buffer preparation to final fill applications.

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A set of three stainless steel single-use mixers on wheels, designed for single-use mixing.
Single-use Mixers

Our complete range of Mobius® single-use mixing solutions can meet your needs for mixing pharmaceutical ingredients from intermediate to final drug products, as well as preparation of process solutions such as buffers and media. 

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The image depicts a series of laboratory bioreactors with varying capacities from 3 L to 2000 L.
Bioprocessing Single-Use Bioreactors

Mobius® single-use bioreactors are scalable, configurable, and reliable, able to perform fed-batch and perfusion bioprocessing at any scale from benchtop to full-scale production.

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The image is a colorful, educational diagram of a cellular process, featuring labeled molecules such as “PLCy”, “RAS”, and “RAF1”, and pathways indicating interactions and reactions within a cell.
Growth Factors and Cytokines

Cytokines and growth factors are critical cell culture media components, particularly when serum-and animal-free conditions or defined media are required. We offer hundreds of purified, recombinant growth factors and cytokines for proliferation, differentiation, angiogenesis studies, and more. 

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