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HPLC Analysis of Tröger′s Base Enantiomers on Astec® Cellulose DMP

HPLC Analysis of Tröger′s Base Enantiomers on Astec® Cellulose DMP application for HPLC

CONDITIONS

column

Astec Cellulose DMP, 15 cm x 4.6 mm I.D., 5 μm particles (51098AST)

mobile phase

[A] heptane; [B] IPA; [C] DEA; (90:10:0.1, A:B:C)

flow rate

0.5 mL/min

column temp.

25 °C

detector

UV, 254 nm

injection

2 μL

sample

2 mg/mL in mobile phase

Description

Application

Tröger′s base is an organic compound that exhibits chirality due to the presence of two bridgehead stereogenic nitrogen atoms in its structure.

Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany