A synergistically enhanced T(1) -T(2) dual-modal contrast agent.

A synergistically enhanced T(1) -T(2) dual-modal contrast agent.

Advanced materials (Deerfield Beach, Fla.) (2012-09-14)

Zijian Zhou, Dengtong Huang, Jianfeng Bao, Qiaoli Chen, Gang Liu, Zhong Chen, Xiaoyuan Chen, Jinhao Gao

ABSTRACT

Monodisperse Gd(2) O(3) -embedded iron oxide (GdIO) nanoparticles can simultaneously enhance the local magnetic field intensities of each other under an external magnetic field and result in synergistic enhancement of T(1) and T(2) effects. GdIO nanoparticles have the unique property to be both T(1) and T(2) contrast agents and can potentially lead to higher accuracy in cancer diagnosis, particularly liver tumors.

MATERIALS

Product Number

Brand

Product Description

48220

Sigma-Aldrich

Gadolinium(III) oxide, ≥99.9%

278513

Sigma-Aldrich

Gadolinium(III) oxide, powder, 99.9% trace metals basis

203297

Sigma-Aldrich

Gadolinium(III) oxide, powder, ≥99.99% trace metals basis

637335

Sigma-Aldrich

Gadolinium(III) oxide, nanopowder, <100 nm particle size (BET), 99.8% trace metals basis