TP63
tumor protein p63
Synonyms:
AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L
Species:
Human TP63 (8626), Rat Tp63 (246334), cow TP63 (615335), sheep TP63 (101108874), sheep TP63 (100048992), domestic guinea pig Tp63 (100732143), naked mole-rat Tp63 (101710600), Zebrafish tp63 (260407), Horse TP63 (100059752), domestic cat TP63 (101095124) ...More
UniProtKB ID:
Gene ID:
- Human(8626) Summary: This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008]
- Rat(246334) tumor protein p63
- cow(615335) tumor protein p63
- sheep(101108874) tumor protein p63
- sheep(100048992) tumor protein p63
- domestic guinea pig(100732143) tumor protein p63
- naked mole-rat(101710600) tumor protein p63
- Zebrafish(260407) tumor protein p63
- Horse(100059752) tumor protein p63
- domestic cat(101095124) tumor protein p63
- chicken(374269) tumor protein p63
- dog(488125) tumor protein p63
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TP63 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL3748, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-p40 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-P40 Antibody, clone 11F12.1, clone 11F12.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-P40 (TP63) Antibody, clone 11H1, clone 11H1, from mouse,
Species Reactivity
human
Application
western blot
Anti-P40 Antibody, clone 11F12.1, Alexa Fluor™ 488, clone 11F12.1, from mouse, ALEXA FLUOR™ 488,
Species Reactivity
human, mouse
Application
immunocytochemistry
Proteins
Product Number
Description
Species
p63, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species