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Merck

TIA1

TIA1 cytotoxic granule-associated RNA binding protein

Synonyms:
TIA-1, WDM
Species:
Human TIA1 (7072), Mouse Tia1 (21841), Rat Tia1 (312510), Zebrafish tia1 (793165), domestic cat TIA1 (101096055), dog TIA1 (610625), chicken TIA1 (771327), cow TIA1 (538533), sheep TIA1 (101105642), naked mole-rat Tia1 (101725408)
UniProtKB ID:
P31483, Q53SS9
Gene ID:
  • Human(7072) Summary: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq, Jul 2008]
  • Mouse(21841) cytotoxic granule-associated RNA binding protein 1
  • Rat(312510) TIA1 cytotoxic granule-associated RNA binding protein
  • Zebrafish(793165) cytotoxic granule-associated RNA binding protein 1
  • domestic cat(101096055) TIA1 cytotoxic granule-associated RNA binding protein
  • dog(610625) TIA1 cytotoxic granule-associated RNA binding protein
  • chicken(771327) TIA1 cytotoxic granule-associated RNA binding protein
  • cow(538533) TIA1 cytotoxic granule-associated RNA binding protein
  • sheep(101105642) TIA1 cytotoxic granule-associated RNA binding protein
  • naked mole-rat(101725408) TIA1 cytotoxic granule-associated RNA binding protein
  • domestic guinea pig(100725919) TIA1 cytotoxic granule-associated RNA binding protein

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2107983
Anti-TIA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
SAB4301803
Anti-TIA1, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
HPA056961
Anti-TIA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
SAB2501039
Anti-TIA1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU158111
MISSION® esiRNA, targeting human TIA1,
Species
human