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Merck

GCHFR

GTP cyclohydrolase I feedback regulator

Synonyms:
GFRP, HsT16933, P35
Species:
Human GCHFR (2644), Mouse Gchfr (320415), Rat Gchfr (171128), Zebrafish gchfr (393735), chicken GCHFR (423003), dog GCHFR (487498), cow GCHFR (617650), domestic cat GCHFR (101088493), sheep GCHFR (101110240), domestic guinea pig Gchfr (100717119)
UniProtKB ID:
P30047, B2R4L6, Q2M1Q2, Q99749
Gene ID:
  • Human(2644) Summary: GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. [provided by RefSeq, Jul 2008]
  • Mouse(320415) GTP cyclohydrolase I feedback regulator
  • Rat(171128) GTP cyclohydrolase I feedback regulator
  • Zebrafish(393735) GTP cyclohydrolase I feedback regulator
  • chicken(423003) GTP cyclohydrolase I feedback regulator
  • dog(487498) GTP cyclohydrolase I feedback regulator
  • cow(617650) GTP cyclohydrolase I feedback regulator
  • domestic cat(101088493) GTP cyclohydrolase I feedback regulator
  • sheep(101110240) GTP cyclohydrolase I feedback regulator
  • domestic guinea pig(100717119) GTP cyclohydrolase I feedback regulator

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA046258
Anti-GCHFR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
SAB1410517
Anti-GCHFR antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
SAB1402206
Monoclonal Anti-GCHFR antibody produced in mouse, clone 4G6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

esiRNA

Product Number
Description
Species
EHU023661
MISSION® esiRNA, targeting human GCHFR,
Species
human
EMU089921
MISSION® esiRNA, targeting mouse Gchfr,
Species
mouse