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Merck

CYLD

cylindromatosis (turban tumor syndrome)

Synonyms:
BRSS, CDMT, CYLD1, CYLDI, EAC, MFT, MFT1, SBS, TEM, USPL2
Species:
UniProtKB ID:
Gene ID:
  • Human(1540) Summary: This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(74256) cylindromatosis (turban tumor syndrome)
  • Rat(312937) cylindromatosis (turban tumor syndrome)
  • fruit fly(34380) cylindromatosis
  • chicken(415725) cylindromatosis (turban tumor syndrome)
  • domestic cat(101094641) cylindromatosis (turban tumor syndrome)
  • cow(536421) cylindromatosis (turban tumor syndrome)
  • Horse(100050308) cylindromatosis (turban tumor syndrome)
  • dog(611649) cylindromatosis (turban tumor syndrome)
  • sheep(101113429) cylindromatosis (turban tumor syndrome)
  • domestic guinea pig(100732328) cylindromatosis (turban tumor syndrome)
  • naked mole-rat(101707343) cylindromatosis (turban tumor syndrome)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CYLD (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
ANTI-CYLD antibody produced in mouse, clone 2G1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
ANTI-CYLD antibody produced in mouse, clone 1E9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
ANTI-CYLD antibody produced in mouse, clone 2F9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-phospho-CYLD Antibody (Ser418), serum, from rabbit,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cyld,
Species
mouse
MISSION® esiRNA, targeting human CYLD,
Species
human