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Merck

CD3D

CD3d molecule, delta (CD3-TCR complex)

Synonyms:
CD3-DELTA, T3D
Species:
UniProtKB ID:
Gene ID:
  • Human(915) Summary: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
  • Mouse(12500) CD3 antigen, delta polypeptide
  • Rat(25710) CD3 molecule, delta
  • chicken(396518) CD3d molecule, delta (CD3-TCR complex)
  • domestic cat(101083107) CD3d molecule, delta (CD3-TCR complex)
  • cow(281053) CD3d molecule, delta (CD3-TCR complex)
  • dog(479419) CD3d molecule, delta (CD3-TCR complex)
  • sheep(443397) CD3d molecule, delta (CD3-TCR complex)
  • domestic guinea pig(100727506) CD3d molecule, delta (CD3-TCR complex)
  • naked mole-rat(101712534) CD3d molecule, delta (CD3-TCR complex)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CD3D antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CD3D antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
proximity ligation assay
western blot
Anti-CD3D antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CD3D,
Species
human