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  • Application of dearomatization strategy on the synthesis of furoquinolinone and angelicin derivatives.

Application of dearomatization strategy on the synthesis of furoquinolinone and angelicin derivatives.

Organic letters (2012-04-07)
Yang Ye, Li Zhang, Renhua Fan
ABSTRACT

The oxidative dearomatization of 3-(3-alkynyl-4-hydroxyphenyl)propanoic acid is combined with a cascade transition-metal catalyzed cyclization/addition/aromatization/lactamization sequence, which provides a novel approach to prepare furoquinolinone and angelicin derivatives in a convergent and efficient manner.