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  • Quantification of estragole in fennel herbal teas: implications on the assessment of dietary exposure to estragole.

Quantification of estragole in fennel herbal teas: implications on the assessment of dietary exposure to estragole.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association (2010-11-26)
Antonio Raffo, Stefano Nicoli, Catherine Leclercq
ABSTRACT

Quantification of estragole content in commercial fennel herbal teas was carried out in order to allow for a more accurate estimate of the dietary exposure to estragole. A simple and rapid analytical method, based on Stir Bar Sorptive Extraction and GC-MS, was developed for this purpose. Fennel teas obtained from different types of commercial products were analysed. Concentration levels ranged from 241 to 2058 μg L(-1) in teas from teabags, from 9 to 912 μg L(-1) in diluted instant teas, from 251 to 1718 μg L(-1) in teas from not packaged seeds. Based on these data and considering the daily consumption of three portions of herbal tea, a maximum exposure to estragole for adults of 10 μg/kg bw/day was calculated. The relatively high level observed in diluted instant teas of some brands deserves attention since these products are designed for infant consumption. Estimated exposure in infants was up to 51 μg/kg bw/day for teas from teabags, and up to 23 μg/kg bw/day for instant teas. A generalization of the use of suitable technologies in production processes of instant teas could substantially reduce the exposure to estragole in the vulnerable population groups (infants, young children, pregnant and breastfeeding women) who consume these products.

MATERIALS
Product Number
Brand
Product Description

Supelco
Estragole, analytical standard
Sigma-Aldrich
4-Allylanisole, ≥98%, FCC
Sigma-Aldrich
4-Allylanisole, 98%