- Lipase catalysed synthesis of optically enriched alpha-haloamides.
Lipase catalysed synthesis of optically enriched alpha-haloamides.
Bioorganic & medicinal chemistry (2001-05-30)
A Azim, S K Sharma, C E Olsen, V S Parmar
PMID11377191
ABSTRACT
An efficient lipase catalysed synthesis of optically enriched alpha-halogenated amides with concomitant optical enrichment of the starting alpha-haloesters is described. Candida antarctica lipase (CAL) was found to be a better catalyst over porcine pancreatic lipase (PPL) and Candida cylindracea lipase (CCL). The effect of different organic solvents was also studied.
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Diisopropyl ether, anhydrous, 99%, contains either BHT or hydroquinone as stabilizer
Sigma-Aldrich
Diisopropyl ether, ReagentPlus®, 99%, contains either BHT or hydroquinone as stabilizer
Sigma-Aldrich
Diisopropyl ether, contains either BHT or hydroquinone as stabilizer, ACS reagent, ≥99.0%
Sigma-Aldrich
Diisopropyl ether, contains either BHT or hydroquinone as stabilizer, ACS reagent, ≥99.0%