Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

I1145

Sigma-Aldrich

Interleukin-5 from mouse

≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture

Synonym(s):

IL-5

Sign Into View Organizational & Contract Pricing

Select a Size

5000 UNITS
$515.46
10000 UNITS
$879.67
25000 UNITS
$2,044.90

$515.46

Estimated to ship onMay 17, 2025

All Photos(1)

Select a Size

Change View
5000 UNITS
$515.46
10000 UNITS
$879.67
25000 UNITS
$2,044.90

About This Item

MDL number:
MFCD00131402
UNSPSC Code:
12352202
NACRES:
NA.32

$515.46

Estimated to ship onMay 17, 2025

biological source

mouse

Quality Level

200

recombinant

expressed in baculovirus infected Sf21 cells

Assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

0.04-0.30 ng/mL EC50

mol wt

45-50 kDa

packaging

pkg of 5 μg

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
M5760N5908810213P
10074-G5 ≥98% (HPLC)

G3798

10074-G5

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan

M5760

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan

N-(NBD-Aminocaproyl)sphinganine ≥98%

N5908

N-(NBD-Aminocaproyl)sphinganine

C12-NBD Sphinganine Avanti Research™ - A Croda Brand 810213P, powder

810213P

C12-NBD Sphinganine

assay

≥98% (HPLC)

assay

>97.5% (HPLC)

assay

≥98%

assay

>99% (TLC)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

-

storage temp.

room temp

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: >10 mg/mL

solubility

DMSO:methanol (1:1): 50 mg/mL, clear, orange

solubility

-

solubility

-

color

red

color

orange to red

color

-

color

-

Biochem/physiol Actions

Exhibits activity on eosinophils, B cells, and thymocytes.
Interleukin-5 exhibits activity on eosinophils, B cells, and thymocytes. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.
Interleukin-5 is a product of activated T lymphocytes and exhibits activity on eosinophils, B cells and thymocytes. Synonyms or biological activities attributed to IL-5 include: EDF (eosinophil differentiating factor), BCGF-II (B cell growth factor-II), TRF (T cell replacing factor), IgA-EF (IgA enhancing factor) and EO-CSF (eosinophil colony stimulating factor). Natural IL-5 is a 45-50 kDa dimeric glycoprotein, although glycosylation is not required for activity. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    SLBX1157
    091M1192V
    051M1338V
    050M1558
    029K1234

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Stefan Rebhandl et al.
    European journal of immunology, 44(7), 2175-2187 (2014-03-29)
    Activation-induced deaminase (AID) is a DNA-mutating enzyme that mediates class-switch recombination as well as somatic hypermutation of antibody genes in B cells. Due to off-target activity, AID is implicated in lymphoma development by introducing genome-wide DNA damage and initiating chromosomal
    Yuan Wang et al.
    Journal of immunology (Baltimore, Md. : 1950), 195(3), 1171-1181 (2015-06-28)
    Complement is implicated in asthma pathogenesis, but its mechanism of action in this disease remains incompletely understood. In this study, we investigated the role of properdin (P), a positive alternative pathway complement regulator, in allergen-induced airway inflammation. Allergen challenge stimulated
    Xiang Zhu et al.
    American journal of physiology. Gastrointestinal and liver physiology, 306(11), G974-G982 (2014-04-20)
    Extracellular acidification has been observed in allergic inflammatory diseases. Recently, we demonstrated that the proton-sensing receptor G protein-coupled receptor 65 (GPR65) regulates eosinophil survival in an acidic environment in vitro and eosinophil accumulation in an allergic lung inflammation model. For
    Chisa Nakashima et al.
    The Journal of allergy and clinical immunology, 134(1), 100-107 (2014-04-10)
    Although eosinophils have been detected in several human skin diseases in the vicinity of basophils, how eosinophils infiltrate the skin and the role of eosinophils in the development of skin inflammation have yet to be examined. Using murine irritant contact

    Articles

    Interleukin Family (IL)

    The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages and monocytes and plays a key role in inflammatory and immune responses and may induce anti-tumor immunity.

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service