GF172
FGF-10 Protein, Human Recombinant, 25µg
The Fibroblast Growth Factors (FGFs) are heparin binding glycoproteins that exert a variety of biological activities toward cells of mesenchymal, neuronal & epithelial origin.
Synonym(s):
FGF10, Fibroblast Growth Factor 10, Keratinocyte growth factor 2
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.75
Recommended Products
General description
The Fibroblast Growth Factors (FGFs) are heparin binding glycoproteins that exert a variety of biological activities toward cells of mesenchymal, neuronal, and epithelial origin. FGF10 belongs to the subgroup of FGFs that also includes FGF3, 7, and 22. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-10 is most related to KGF/FGF-7 and is expressed during the development and preferentially in adult lungs. It signals through the FGFR 2b. Recombinant human FGF-10 is a 19.3 kDa protein consisting of 170 amino acid residues.
Quality
Bioactivity assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF− receptors is = 0.5 ng/ml, corresponding to a specific activity of = 2 × 106 units/mg.
Bioactivity assay #2: Determined by a cell proliferation assay using 4MBr-5 cells. The expected−ED50−for this effect is 0.5−15.0 ng/ml.
Bioactivity assay #2: Determined by a cell proliferation assay using 4MBr-5 cells. The expected−ED50−for this effect is 0.5−15.0 ng/ml.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service