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05-938

Sigma-Aldrich

Anti-ORC6 Antibody, clone 3A4

clone 3A4, Upstate®, from rat

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rat

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

3A4, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

ChIP: suitable
western blot: suitable

isotype

IgG2a

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ORC6(23594)

Specificity

ORC6

Immunogen

Full-length human origin recognition complex 6 (ORC6). Clone 3A4.

Application

Anti-ORC6 Antibody, clone 3A4 is a high quality Rat Monoclonal Antibody for the detection of ORC6 & has been validated in ChIP & WB.

Quality

Routinely evaluated by immunoblot.

Target description

30kDa A non specific protein was also detected at Mr 120kDa

Physical form

Format: Purified

Analysis Note

Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Complex protein-DNA dynamics at the latent origin of DNA replication of Epstein-Barr virus.
Ritzi, Marion, et al.
Journal of Cell Science, 116, 3971-3984 (2003)
Aparna Palakodeti et al.
Human molecular genetics, 19(1), 99-110 (2009-10-10)
Chromosomal common fragile sites (CFSs) are genetically unstable regions of the genome that are induced by conditions that impair DNA replication. In this report, we show that treatment with the DNA polymerase inhibitor, aphidicolin (APH), slows the replication rate throughout

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