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Merck

TXNRD3

thioredoxin reductase 3

Synonyms:
TGR, TR2, TRXR3
Species:
UniProtKB ID:
Gene ID:
  • Human(114112) Summary: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
  • Mouse(232223) thioredoxin reductase 3
  • Rat(297437) thioredoxin reductase 3
  • Zebrafish(352925) thioredoxin reductase 3
  • Horse(100060514) thioredoxin reductase 3
  • domestic cat(101090928) thioredoxin reductase 3
  • dog(484619) thioredoxin reductase 3
  • chicken(416031) thioredoxin reductase 3
  • cow(319097) thioredoxin reductase 3
  • sheep(101117116) thioredoxin reductase 3
  • Domestic Rabbit(100358257) thioredoxin reductase 3
  • domestic guinea pig(100719286) thioredoxin reductase 3

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TXNRD3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TXNRD3,
Species
human
MISSION® esiRNA, targeting mouse Txnrd3,
Species
mouse