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Merck

SOX2

SRY (sex determining region Y)-box 2

Synonyms:
ANOP3, MCOPS3
Species:
Human SOX2 (6657), Mouse Sox2 (20674), Rat Sox2 (499593), Zebrafish sox2 (378723), Horse SOX2 (100146979), domestic cat SOX2 (100379629), dog SOX2 (488092), chicken SOX2 (396105), cow SOX2 (784383), Goat SOX2 (100861576) ...More
UniProtKB ID:
P48431, Q14537
Gene ID:
  • Human(6657) Summary: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
  • Mouse(20674) SRY-box containing gene 2
  • Rat(499593) SRY (sex determining region Y)-box 2
  • Zebrafish(378723) SRY-box containing gene 2
  • Horse(100146979) SRY (sex determining region Y)-box 2
  • domestic cat(100379629) SRY (sex determining region Y)-box 2
  • dog(488092) SRY (sex determining region Y)-box 2
  • chicken(396105) SRY (sex determining region Y)-box 2
  • cow(784383) SRY (sex determining region Y)-box 2
  • Goat(100861576) SRY (sex determining region Y)-box 2
  • sheep(101110563) SRY (sex determining region Y)-box 2
  • domestic guinea pig(100714747) SRY (sex determining region Y)-box 2
  • naked mole-rat(101723266) SRY (sex determining region Y)-box 2

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Antibodies

Product Number
Description
Species Reactivity
Application
ZRB5603
Anti-Sox-2 Antibody, clone 1A2, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunohistochemistry
western blot
SAB2701800
Anti-sox2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
zebrafish
Application
immunohistochemistry
western blot
AV38232
Anti-SOX2 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, goat, human, mouse, pig, rat
Application
western blot
AB5603
Anti-Sox2 Antibody, Chemicon®, from rabbit,
Species Reactivity
bovine, human, mouse, rat, rhesus macaque
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
SAB5700644
Anti-SOX2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot

Proteins

Product Number
Description
Species
SRP3158
Sox2 TAT human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human
SRP3157
Sox2 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
EHU184131
MISSION® esiRNA, targeting human SOX2,
Species
human