SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
Synonyms:
PI12, neuroserpin
Species:
Human SERPINI1 (5274), Mouse Serpini1 (20713), Rat Serpini1 (116459), Zebrafish serpini1 (557627), dog SERPINI1 (478684), domestic cat SERPINI1 (101090383), Horse SERPINI1 (100057410), chicken SERPINI1 (425002), Domestic Rabbit SERPINI1 (100341797), naked mole-rat Serpini1 (101716288) ...More
UniProtKB ID:
Gene ID:
- Human(5274) Summary: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Mouse(20713) serine (or cysteine) peptidase inhibitor, clade I, member 1
- Rat(116459) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- Zebrafish(557627) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- dog(478684) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- domestic cat(101090383) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- Horse(100057410) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- chicken(425002) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- Domestic Rabbit(100341797) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- naked mole-rat(101716288) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- domestic guinea pig(100733658) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- cow(509976) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- sheep(101122566) serpin peptidase inhibitor, clade I (neuroserpin), member 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SERPINI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-SERPINI1, (C-terminal) antibody produced in mouse, clone 1E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-SERPINI1 antibody produced in mouse, clone 1D10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SERPINI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Neuroserpin antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
chimpanzee, human, mouse, rat
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species
Neuroserpin human, recombinant, expressed in E. coli, ≥96% (SDS-PAGE), ≥96% (HPLC), suitable for cell culture,
Species
human