NEFL
neurofilament, light polypeptide
Synonyms:
CMT1F, CMT2E, NF-L, NF68, NFL
Species:
Human NEFL (4747), Mouse Nefl (18039), Rat Nefl (83613), chicken NEFL (419528), cow NEFL (281348), domestic cat NEFL (101081039), dog NEFL (477378), naked mole-rat Nefl (101704332), domestic guinea pig Nefl (100731797), sheep NEFL (101119539)
UniProtKB ID:
Gene ID:
- Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
- Mouse(18039) neurofilament, light polypeptide
- Rat(83613) neurofilament, light polypeptide
- chicken(419528) neurofilament, light polypeptide
- cow(281348) neurofilament, light polypeptide
- domestic cat(101081039) neurofilament, light polypeptide
- dog(477378) neurofilament, light polypeptide
- naked mole-rat(101704332) neurofilament, light polypeptide
- domestic guinea pig(100731797) neurofilament, light polypeptide
- sheep(101119539) neurofilament, light polypeptide
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NEFL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Neurofilament (2F11) Mouse Monoclonal Antibody, ,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-NEFL antibody produced in mouse, clone 2G10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
flow cytometry
immunofluorescence
immunohistochemistry
western blot
Anti-phospho-NFL (Ser473) Antibody, clone 4F8, clone 4F8, from mouse,
Species Reactivity
bovine, human, mouse, porcine, rat, rhesus macaque
Application
immunohistochemistry
western blot
western blot
Anti-NEFL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
esiRNA
Product Number
Description
Species