LEP
leptin
Synonyms:
LEPD, OB, OBS
Species:
Human LEP (3952), Mouse Lep (16846), Rat Lep (25608), fruit fly lep (5658637), cow LEP (280836), Horse LEP (100034042), domestic cat LEP (493838), dog LEP (403616), Thale Cress LEP (831238), chicken LEP (373955) ...More
UniProtKB ID:
Gene ID:
- Human(3952) Summary: This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008]
- Mouse(16846) leptin
- Rat(25608) leptin
- fruit fly(5658637) leprechaun
- cow(280836) leptin
- Horse(100034042) leptin
- domestic cat(493838) leptin
- dog(403616) leptin
- Thale Cress(831238) ethylene-responsive transcription factor LEP
- chicken(373955) leptin
- domestic guinea pig(100716751) leptin
- naked mole-rat(101722703) leptin
- Goat(100860794) leptin
- Domestic Rabbit(100008747) leptin
- sheep(443534) leptin
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Lep Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-LEP antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, goat, horse, human, mouse, rat, sheep
Application
immunohistochemistry
western blot
western blot
Anti-Leptin antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
western blot
Proteins
Product Number
Description
Species
Leptin human, ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder,
Species
human
Leptin from rat, ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder,
Species
rat
Leptin from mouse, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder,
Species
mouse
esiRNA
Product Number
Description
Species