GPC3
glypican 3
Synonyms:
DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1
Species:
Human GPC3 (2719), Mouse Gpc3 (14734), Rat Gpc3 (25236), domestic guinea pig Gpc3 (100726246), sheep GPC3 (101119285), Domestic Rabbit GPC3 (100351858), Zebrafish gpc3 (387365), cow GPC3 (615239), domestic cat GPC3 (101094739), dog GPC3 (481056)
UniProtKB ID:
Gene ID:
- Human(2719) Summary: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
- Mouse(14734) glypican 3
- Rat(25236) glypican 3
- domestic guinea pig(100726246) glypican 3
- sheep(101119285) glypican 3
- Domestic Rabbit(100351858) glypican 3
- Zebrafish(387365) glypican 3
- cow(615239) glypican 3
- domestic cat(101094739) glypican 3
- dog(481056) glypican 3
- chicken(770863) glypican 3
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Human Glypican 3 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GPC3 antibody produced in mouse, clone 2C12, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-Glypican-3 antibody, Rabbit monoclonal, clone SP86, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Glypican-3 (1G12) Mouse Monoclonal Antibody, clone 1G12, unconjugated, Cell Marque™,
Species Reactivity
human
Application
immunohistochemistry
Anti-GPC3, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-GPC3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry