Skip to Content
Merck

C8B

complement component 8, beta polypeptide

Synonyms:
C82
Species:
UniProtKB ID:
Gene ID:
  • Human(732) Summary: This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
  • Mouse(110382) complement component 8, beta polypeptide
  • Rat(313421) complement component 8, beta polypeptide
  • Zebrafish(793127) complement component 8, beta polypeptide
  • chicken(424669) complement component 8, beta polypeptide
  • cow(513217) complement component 8, beta polypeptide
  • Horse(100059423) complement component 8, beta polypeptide
  • domestic cat(101099229) complement component 8, beta polypeptide
  • dog(479555) complement component 8, beta polypeptide
  • sheep(101102522) complement component 8, beta polypeptide
  • Domestic Rabbit(100009385) complement component 8, beta polypeptide
  • domestic guinea pig(100729610) complement component 8, beta polypeptide
  • naked mole-rat(101696501) complement component 8, beta polypeptide

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-C8B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-C8B (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human C8B,
Species
human