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A novel method for dengue virus detection and antibody screening using a graphene-polymer based electrochemical biosensor.

Nanomedicine : nanotechnology, biology, and medicine (2016-08-26)
Krongkaew Navakul, Chompunuch Warakulwit, Pa-Thai Yenchitsomanus, Aussara Panya, Peter A Lieberzeit, Chak Sangma
RESUMEN

Dengue fever is a major disease that kills many people in the developing world every year. During early infection, a patient displays a high temperature without other signs. After this stage, and without proper treatment, serious damage to internal organs can happen, which occasionally leads to death. A rapid technique for the early detection of dengue virus (DENV) could reduce the number of fatalities. This study presents a new technique for the detection, classification and antibody screening of DENV based on electrochemical impedance spectroscopy (EIS). We found that the charge transfer resistance (R

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N,N′-(1,2-Dihydroxyethylene)bisacrylamide, 97%