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Merck

The metabolism of ethosuximide.

European journal of drug metabolism and pharmacokinetics (1993-10-01)
J S Millership, J Mifsud, P S Collier
RESUMEN

The metabolism of the antiepileptic drug ethosuximide (3-ethyl-3-methylpyrollidine-2,5-dione) (I) in animals and humans is reviewed. Chiral aspects of the metabolism of ethosuximide are discussed. Clarification of the precise nature of the hydroxymetabolites of ethosuximide is presented.

MATERIALES
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Sigma-Aldrich
Ethosuximide
Supelco
Ethosuximide, Pharmaceutical Secondary Standard; Certified Reference Material
Ethosuximide, European Pharmacopoeia (EP) Reference Standard