- Novel tricyclic benzothiazolo[2,3-c]thiadiazine antagonists of the platelet ADP receptor (P2Y(12)).
Novel tricyclic benzothiazolo[2,3-c]thiadiazine antagonists of the platelet ADP receptor (P2Y(12)).
Bioorganic & medicinal chemistry letters (2001-07-19)
R M Scarborough, A M Laibelman, L A Clizbe, L J Fretto, P B Conley, E E Reynolds, D M Sedlock, H Jantzen
PMID11459636
RESUMEN
Novel non-nucleoside tricyclic platelet ADP receptor (P2Y(12)) antagonists have been discovered that bind reversibly and with high affinity to the platelet receptor. Condensation of various 2-aminobenzothiazoles with chlorosulfonylacetyl chloride affords these novel tricyclic heterocycles, which are novel and unpredicted products of this reaction.
MATERIALES
Referencia del producto
Marca
Descripción del producto